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Korean J Urol Oncol > Volume 13(3); 2015 > Article
The Korean Journal of Urological Oncology 2015;13(3): 105-108.
만성전립선염/만성골반통증후군에서 신경병성 통증
이승주
가톨릭대학교 의과대학 비뇨기과학교실
Neuropathic Pain in Chronic Prostatitis/Chronic Pelvic Pain Syndrome(CP/CPPS)
Seung-Ju Lee
Department of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea
Published online: December 30, 2015.
ABSTRACT
Chronic prostatitis/chronic pelvic pain syndrome(CP/CPPS) has been a frustrating condition that is characterized by pain in areas including the perineum, rectum, prostate, penis, testicles, and abdomen. Unfortunately, effective treatment for the chronic pelvic pain remains uncertain and most urologists still believe we have little to offer these patients once traditional therapy including antibiotics has failed. Proposed mechanisms in development of pain in CP/CPPS is that biological insult in the context of alterations in psychoimmunoneurendocrine factors produces the chronic pain experience. There is increasing evidence that the chronic pain is associated with long-lasting changes both to the structure and function of the nervous system. Nerve injury, such as in neuropathic pain, peripheral sensitization, and central sensitization might play an important role in CP/CPPS and therefore be a therapeutic target. Newer medications, such as the anticonvulsant gabapentin and pregabalin, are becoming increasingly used for neuropathic pain in CP/CPPS. Now, urologists should understand the neuropathic pain in CP/CPPS and become on some level a pain doctor. (Korean J Urol Oncol 2015;13:105-108)
Key Words: Prostatitis; Neuropathic pain; Anticonvulsant
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