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Korean J Urol Oncol > Volume 6(2); 2008 > Article
The Korean Journal of Urological Oncology 2008;6(2): 68-73.
방광암에서의 분자표지자
윤석중, 김원재
충북대학교 의과대학 비뇨기과학교실
Molecular Marker in Bladder Cancer
Seok Joong Yun , Wun-Jae Kim
Department of Urology, College of Medicine, Chungbuk National University, Cheongju, Korea
Published online: August 30, 2008.
ABSTRACT
Bladder cancer has a variety of natural courses, and numerous factors are related to their recurrence, progression, and survival. Because of the need for long-term and frequent follow-up, as well as the paucity of sensitive and specific noninvasive tests, bladder cancer ranks as the most bothersome condition to patients, and even urologists. None of the biomarkers reported to date have shown sufficient sensitivity and specificity for detecting the whole spectrum of bladder cancer diseases in routine clinical practice. However, recent advance in biomarker technologies, such as gene expression analysis, microarray, and epigenetic studies will provide us to identify the promising bladder cancer marker. Herein, I review the recent advance in molecular marker identification for bladder cancer. (Korean J Urol Oncol 2008;6:68-73)
Key Words: Urinary bladder neoplasm; Molecular marker; Biologic tumor
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